Thursday , January 28 2021

Is microbial and cancer connected? $ 25 million is a target to find projects




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Microbial is believed to be more likely to be associated with cancer. US The new multi-million-dollar project, led by the researchers, aims to investigate this link of colorectal cancer. & Nbsp; Photo credit: Getty Royalty FreeGetty

Microbial is presently attached to every aspect of our health and is now one of the world's largest cancer charities, Cancer Research UK It is dedicated to $ 25 million to find out if it can be in colorectal cancer, Third most common US Cancer in

There are many lifestyle factors that affect the risk of developing colorectal cancer. Researchers discover that the effect of several factors on microbialism, such as diet and obesity, also play an important role in reaction to colorectal cancer, progress and cancer medicines.

This Ambitious project Six researchers are spread among six separate countries, but jointly two U.S. Leads by researchers; Dana-Faber Cancer Institute professor Matthew Marerson and Harvard Medical School professor Wendy Garrett and Harvard T.H. The Chan School of Public Health. Mayerson is an expert in cancer genetics and Garrett's skills are immunology and infectious diseases.

"The colon is the most populous microbial environment on the planet. Our nodes and cancers also serve microbial malpractices that contribute to the drug's reaction or not. About cancer, risk, development, treatment and care of microbial lenses There are huge opportunities of thinking, "Garrett said.

One is called bacterial species Helicopter pilot Has long been accepted due to stomach cancer, but its link to colorectal cancer is uncertain, though there Increasing evidence To indicate that it is involved in some cases. There is a lot of interest in bacteria found in the common intestinal microbial, which is currently not considered to have any role in the disease.

"We and others have shown that bacteria can promote colon cancer in many model systems, and it is possible to limit the growth of this colon cancer if you use this infection. We currently do not understand this detail and there is enough evidence for this to happen among the people. That's why. " Meyerson said.

The team uses a variety of experimental systems which include animal ties and potential relationships between bacteria and colorectal cancer. Organoids; Small organs in a burger Cologne is made from patients with cancer. The team will also see the effect of current treatment for colorectal cancer on Microbial by collecting samples from patients receiving treatment.

"With new genetic technologies, we can map microbial unreliable detail, so now it is time to investigate this incident of cancer. With this information, we hope to develop new microbial-targeted therapies for colorectal cancer," said Meyersson.

This work is only from the beginning and the time will come when the team reaches a point where there is sufficient evidence that Microbiol is associated with colorectal cancer, it may consider trying to change the disease to prevent or prevent the disease, but they are well set. If the initial data is contingent, then to perform this task.

"First of all we need to take security with any kind of interference. We have many clinical trials involved in the study and the entire clinical trial network supporting this network and is ready to jump," Garrett said.

Dr. Amitabh Bachchan Matthew Meyersen and Dr. Will be headed by Wendy Garrett.Sam Ogden, photographer Dana-Fiber Cancer Institute

Cancer Research UK, which is a historically funded researcher based in UK hospitals and universities, is now called & # 39; Grand Challenges & # 39; , Which is involved in linking some of the biggest challenges in cancer research to traditional solutions, with the latest solutions.

"The Grand Challenge of Cancer Research UK has been established separately from all other research funding, in which it aims to focus on the specific challenges in cancer research, and to bring bright minds from various topics around the world. We receive 134 applications from 41 different countries. Which had narrowed down in the last three projects for this year's funding round, "INF Lkeksa, PhD, Cancer Research UK, said the executive director of research and innovation.

The other two projects focus on finding new ways to cope with cancer due to chronic inflammation and give a more complete understanding of why cancer is increasing in some tissues, but not in others. US Both of them are funded by the researchers located in a total of $ 75 million for three projects.

"Cancer is a global problem that needs a global solution. The quality of the apps proves that the best science occurs when the world's top scientists work together," said Faulkas.

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Microbial is believed to be more likely to be associated with cancer. US The new multi-million-dollar project, led by the researchers, aims to investigate this link of colorectal cancer. Photo credit: Getty Royalty FreeGetty

Microbial is presently associated with every aspect of our health and is now one of the world's largest cancer charities; Cancer Research UK has dedicated $ 25 million to be involved in colorectal cancer, it is the third most common cancer. US

There are many lifestyle factors that affect the risk of developing colorectal cancer. Researchers discover that the effect of several factors on microbialism, such as diet and obesity, also play an important role in reaction to colorectal cancer, progress and cancer medicines.

The ambitious project consists of 14 investigators spread across six different countries, but jointly created by the U.S. researchers; Dana-Faber Cancer Institute professor Matthew Marerson and Harvard Medical School professor Wendy Garrett and Harvard T.H. The Chan School of Public Health. Mayerson is an expert in cancer genetics and Garrett's skills are immunology and infectious diseases.

"The colon is the most populous microbial environment on the planet, and our nodes and cancers can also be involved in capturing microbes that contribute to the drug's reaction," says Garrett, who says cancer, risk, development, treatment and cancer. There is a great opportunity to think about microscopy lenses through care.

One is called bacterial species Helicopter pilot Has long been accepted due to stomach cancer, but its link to colorectal cancer is uncertain, although in some cases there is increasing evidence to suggest that it is involved. There is a lot of interest in bacteria found in the common intestinal microbial, which is currently not considered to have any role in the disease.

"We and others have shown that bacteria can promote colon cancer in many model systems and if you treat this infection it is possible to limit the growth of this colon cancer. We really understand this in detail or not, enough evidence for this to happen among people. "Said Meyersson.

The team will use a variety of experimental systems, which will investigate possible relationships between bacteria and colorectal cancer, including animal models and organocytes; Small organs in a dish made from patients with colon cancer. The team will also see the effect of current treatment for colorectal cancer on Microbial by collecting samples from patients receiving treatment.

"With new genetic technologies, we can map microbial unreliable detail, so now it's time to investigate this incident of cancer. With this information, we hope to develop new microbial-targeted therapies for colorectal cancer," says Meyersson.

This work is only from the beginning and the time will come when the team reaches a point where there is sufficient evidence that Microbiol is associated with colorectal cancer, it may consider trying to change the disease to prevent or prevent the disease, but they are well set. If the initial data is contingent, then to perform this task.

"First of all, we need to take into consideration security with any kind of interference. We have many clinical trials involved in this study and there is a complete clinical trial network supporting this network and it is ready to jump in," Garrett said.

Dr. Amitabh Bachchan Matthew Meyersen and Dr. Will be headed by Wendy Garrett.Sam Ogden, photographer Dana-Fiber Cancer Institute

Cancer Research UK, which is a historically funded researcher based in UK hospitals and universities, is now called & # 39; Grand Challenges & # 39; , Which is involved in linking some of the biggest challenges in cancer research to traditional solutions, with the latest solutions.

"The Grand Challenge of Cancer Research UK has been established separately from all other research funding, in which it aims to focus on specific challenges in cancer research and to bring together bright minds from various topics around the world. Executive Director of Research Research UK Research and Research , Ian Folkes said that we received 134 applications in 41 different countries E, which has been narrowed down to the final three projects this year's funding round.

The other two projects focus on finding new ways to cope with cancer due to chronic inflammation and give a more complete understanding of why cancer is increasing in some tissues, but not in others. US Both of them are funded by the researchers located in a total of $ 75 million for three projects.

"Cancer is a global problem that needs a global solution. The quality of the apps proves that best science happens when the best scientists work together," Faulkas said.


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