Hormones released during exercise can improve brain health and reduce the loss and memory of dementia, a new study has said.
The study published in Nature Medicine this month included mice, but its findings can help to explain how, at the molecular level, exercise protects our brain, and preserves memory and thinking skills, even among those whose Pasta is spreading.
Significant scientific evidence has already shown that exercise regenerates the brain and affects the thinking.
Researchers have shown in rats and rats that the hippocampus ramps to form new brain cells, which are a part of the brain dedicated to memory composition and collection.
Exercise can improve the health and function of infection between neurons, which allow brain cells to communicate better.
Epidemiological research suggests that physically active alleviating the risk of Alzheimer's disease and other dementias can slow the growth of the disease.
But how many questions are exercised only in the internal action of the brain and these effects are the result of changes in the elsewhere in the body that are good for the brain or there are many questions about the changes in the brain really.
At that point the attention was drawn to the international association of scientists, some neuroscientists, other cell biologists, all of whom focused on preventing, treating and understanding Alzheimer's disease.
Those worries brought an Iranian name hormone in the area of their interest.
Irisin, first known in 2012 and is named for the messenger iris of the gods in Greek mythology, is made by the muscles during exercise.
Hormone starts to jump multiple biochemical reactions across the body, most of which are associated with energy metabolism.
Because alzheimer's disease is believed to be involved, in part, how the cells in the brain use energy, scientists argue that exercise can help protect the brain by increasing the level of irisin.
But if so, they understood, in the human brain, Irisin must exist. To see it, they gathered tissues from the brain banks and using modern testing, found Irisin.
The gene expression pattern in those tissues also suggests that most of these irisins have been made in the brain.
When people died, levels of hormones that were released from dementia were particularly high, but were rarely findable in the brains of people who died with Alzheimer's.
Those tests, however, despite interesting, could not tell the scientists what role Irisin can play in the brain. So researchers now turned to mice, some healthy and others started developing alzheimer's mice form.
They breached the brains of the animals raised for the dementia with the concentration of irrigated Irisina. The mouse begins to perform better on the memory tests soon and shows signs of improved synaptic health.
At the same time, they prevent the production of irisins in the healthy animals brain, and then pump in the form of beta emyloid, it is a protein that combines to create plaques in the brain with Alzheimer's. Effectively, they gave mice to dementia.
And, without any irisin in their brain, once a healthy rat immediately showed signs of poor performance and worse performance in the coordination between the neuron in their hippocampus.
Scientists also looked at healthy neurons within the individual neuron and saw that when they add delirium to the cells, the gene expression is changed in a way that is expected to reduce the losses caused by beta emyloid.
Finally and perhaps most importantly, scientists worked a healthy mice, swimming for about an hour for about five weeks.
In advance, some of the animals were also believed to be substances that block the production of irisin.
In untreated animals, the IRS levels of the brain were exposed to its effects during exercise training and after, after exposure to the brain of beta emyloid, which performed significantly better on memory control, such as balanced control mice have been declared .
But the animals who were unable to make irisins did not get much benefit from exercise. After exposure to beta amyloid, they performed poorly on memory tests as the sedentary animals with beta-emyloid in their brain.
The experiments suggest that these experiments suggest that by increasing the amount of delirium in the brain, it can protect against dementia in the exercise part, Professor Ottavio Arenasio, a professor of pathology and cell biology at Columbia University, said that with the research, the University of Rio de Janeiro's Federal University in Brazil, Queen University in Canada and Two dozen comrades of other organizations.
But experiments use elaborate and multipranged mice, and so we can not say that exercise and irisin work equally among people, or how much exercise and exercise may be best for brain health.
The results also do not show that exercise and irisine can prevent alzheimer's, but only after that begins some symptoms of the disease seem to be similar in the rat.
Scientists involved in this study will soon hope to expect the treatment of dementia in animals and ultimately the people, especially those who have lost their ability to exercise, to investigate the pharmacological form of Irisina, Earney says.
But now, he says, a study lesson will seem like "If you can, go for a walk."