Glasgow University, by Connor Bamford
Approximately two years ago, I showed positive results at the same time – for the first time – it could work the world's most desperate virus, vaccine against Ebola. I had been writing since the epidemic since 2013, when Guinea, Liberia and Sierra Leone were hit. Since then, the disease has spread to three more: all in the Democratic Republic of Congo (DRC).
The first two outbreaks (in 2017 and 2018) were experienced by DRC in preventing Ebola quickly. When a new eruption broke out earlier this year, I also said that it would be quickly brought under control with the use of the vaccine. But that's not the case: The recent spread has been going on since last months, which infects 505 people and by the middle of December 2018, 296 people have been killed.
Why is Ebola proving so great in our best efforts to stop it? The answer is partly with the inherently deadly properties of the Ebola virus. DRC's instability is the second part of the problem.
Ebola: One of the worst viruses
Ebola is a terrible disease. It causes fever, vomiting and diarrhea and bleeding, and it is the most dangerous infection known in medical science. At least half people get the disease – even with the best medical care.
The spread of the virus is closely related to human behavior. It is broadcast by contact with physiologic discharge from anyone who is already ill with Ebola. This means that people who are sick and die, such as close family members or healthcare workers, may be infected.
This close relationship with basic human social biology can dramatically interfere with the family community and regional life. These are only collected by trade and travel restrictions which are often enforced by the surrounding nations.
There is no remedy
Now there is a safe and effective Ebola vaccine, RVSV-Zebovi. But there is one reason that Ebola is so deadly and terrible that it is not a solution. Some of the symptoms are medical treatments, such as fluid loss, pain and fever – but no disease that can completely eliminate the disease.
This lack of therapy suggests that researchers and doctors are not trying. Since Ebola has been discovered in late 1970s, scientists from around the world have been studying the virus and identified many ways to prevent infection and disease. But checking for potential new drugs for viruses, which is uncertain as Ebola in humans, is almost impossible.
It has been said that, some experimental drugs are used under compassionate access rules, which can give unwanted medicines to someone close to death. And during the current spread, the DRC has plans for a series of trials.
Finding a safe and effective remedy for this disease will provide a long way in future emergence.
For now, the best way to get Ebola outbreak is to ensure that the infected person does not pass infection on more than one person.
The "straightforward" way to do this is to find, treat and separate each infected person, then it will track the people who can spread the virus and make sure they do not get sick and then separate them, and Secondly This is helpful in Ebola because it has a relatively long incubation period of about three weeks and it is very clear that you are sick and ill people and their open contacts are sick before they are late.
The existence of RVSV-Zebvovi makes this process more efficient. It can make Ebola more secure and less open to interference. Vaccination is used to immunize and block infections in known people's contacts.
Vaccination approach works well at the time of the outbreak of West Africa and at this time it may be the real reason that this DRC is not infinitely bigger than the outbreak. However, the vaccination process requires many efforts and resources on the ground. Working in larger, more complex, crowded areas – and especially in the case of extended outbreaks – makes this more challenging. What has happened in this DRC? And it is wrong to predict a new outbreak under control. I and others hoped that it is not a restless issue, that the major part of the DRC's east is war wars. This means that contact tracing and vaccination efforts are easily spoiled.
Ebola in the future
Due to the eruption of DRC does not increase the complexity near cities and war zones and the world should not be assimilated. Global efforts must be restored. If it is not, then there is a risk that some will learn to live with Ebola, which never goes away.