The pain is believed to have been initiated by the activation of the free nerve endings without the final organs of the skin. It causes suffering and results in significant costs to society.
About one in every five people experiences persistent pain and there is a significant need to find new painkilling medications. In any case, susceptibility to pain is likewise essential to survival, and it has a protective function. It asks for reflex reactions that will prevent tissue damage, for example, when you feel a jab from a sharp object or you pull your hand away when you burn yourself.
Scientists at the Karolinska Institute in Sweden have discovered another sensory organ that can separate painful mechanical damage, for example, picks and effects.
The newly discovered organ under the skin is susceptible to dangerous environmental inflammation. These include glia cells that have a long protrusion and which go together to form a mesh organ within the skin. This organ is susceptible to painful mechanical damage, for example, picking and pressure.
The organ is linked to the pain-sensitive nerve in the skin, and its activation leads to electrical impulses in the nervous system resulting in the reaction and the experience of pain.
These organs are made up of cells that are very sensitive to mechanical stimulation, which explains how they can participate in the detection of painful pinpricks and pressure. During the experiments, scientists were able to successfully block organs and as a result reduced their ability to experience mechanical pain.
"Our study shows that sensitivity to pain not only occurs in the nerve fibers of the skin, but also in the recently discovered body sensation of the pain," said Patrick Ernfors, professor and chief investigator for the Medical Biochemistry and Biophysics Department of the Carolinska Institute. Change our understanding of the mechanisms Woman, laying, sad and sharp eye of understanding may be important. "
This finding is being published in the journal Science.