Thursday , July 29 2021

Imagine therapy for dementia – How are the key to medical research



Related Article Module – Dimension

The family with Dementia's 50/50 opportunity has discovered the previous discovery and treatment.

Imagine that you are diagnosed with dementia. You have been told that they will gradually deprive you of your thoughts, your personality and your freedom. Now imagine that the doctor says that if your diagnosis has been diagnosed 10 years ago, your condition may be treated, but the damage to your brain is now very extensive.

Prior to a clinical diagnosis of Oakland researcher, Dementia has been given $ 200,000 to further improve the identification of years or decades, hoping that early intervention is possible.

Dr. Brigid Ryan explains, "We are trying to find out the way to determine who is in the early stages of Dementia before having any of these medical symptoms."

"Then the potential treatment that comes with, or it already exists, can be traced among the people.

"Human beings have been treated and failed, we are probably giving them a lot of late. If we can treat it 10 to 20 years ago, perhaps those treatments may be helpful."

Dr. Ryan has been awarded the Auckland Medical Research Foundation Postdoctoral Fellowship, and her 13-year-old team at the University of Oakland is working with the Oakland family, which is a rare part of early dementia that appears in the mid-50s.

The awakened Dementia ran in the family and wanted to help future generations, when Matrix died, he donated a brain center for brain research.

Research has found that its frontotemporal Dementia 1200BC was caused by genetic mutation in Wales. It is also divided by 27 other families around the world, Alzheimer's only other prevalence among dementia people aged 50-65.

Her relatives have a 50/50 chance of getting it. She had four of her six brothers and her father. There are more than 25 children in the next generation, and there are two generations below them. The genetic changes that have been made have not been announced.

"We are working with about 25 people aged 25 to 59. By checking the gene, we can identify people who are healthy today, we know that in 10, 20 or 30 years we know that Dementia," Dr. Ryan says.

"The family members are probably very close to developing the disease due to gene in old age. This is the people in which you can actually say that they will develop Dementia long before developing the clinical symptoms. We are trying to find potential tests which We can identify the early stages of dementia. "

Dr. Ryan's work with this family is unique, because researchers from around the world do not have access to families with genetic changes, instead work with small groups of people.

In order to examine any subtle changes in the research, the need to pass annual tests at the family university, including neuropsychological evaluation on their thinking abilities. They check the feeling of their smell, because there is evidence that they affect the onset of other diseases, such as Alzheimer's and Parkinson. The eye examines changes in the retina and blood tests are carried out to see any markers that can lead to blood tests, which determine the risk of dementia. Alzheimer's research can also be beneficial.

With Demandia's grandmother, Dr. Ryan knows how difficult it is to lose someone whom you love, and keep in mind that it is very difficult to see this before in life.

"It is so much better for these people, because they still raise children, and still have jobs, there is a lot of influence on them.

"Working with this family is really refreshing. It is difficult to come up with knowing people you know. Ultimately this will be the disease, but it is easier to understand that having a personal connection affects dementia seriously.

"Whenever we spend time with any family, we go back to work, because it really makes their input valuable."

Dr. Ryan says that a similarity has he heard that the current dementia treatment aims to throw it out of the forest, while forest fire has already been lit. "We need to stop the fire from appearing for the first time."

By trying to research these family members, the team offers a positive difference yet the best. However, longevity of this project is based solely on funding. Dr. Ryan has estimated that half of his time passes through the lab, while the remaining half part coordinates the team and applying for more grants.

"It is really necessary to support this from the Oakland Medical Research Foundation. We really want to follow the family we can for years, so that we can see what changes are taking place within them because the disease progresses. "

What Is Frontomporal Dementia?

Frontemporal dementia is the second most common type of dementia in 55-65 people, which is just another part of Alzheimer's. It has more enormity of genetic mutation, which means it is likely to pass through generations.

Symptoms include:

• Short-term memory loss
• Behavioral changes – less blocking, loss of social dignity (eg publicly swearing)
• Lack of sympathy
• Immorality for those who enjoyed it
• Invasion / Depression
• Poor personal hygiene

Dr. Ryan says, "Sometimes when you grow up a little bit you'll be going as a strange behavior." "But it quickly becomes clear that it is more serious than that."

Invest in search for therapy

Public donation is necessary to fund funding for medical research. To learn more about research projects invest in the Oakland Medical Research Foundation, go to www.medicalresearch.org.nz.

Ph: 09 923 1701
www.medicalresearch.org.nz


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