Monday , January 25 2021

Biomarkers are known to help diagnose heart conditions



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Researchers have identified two biomarkers who can help diagnose heart conditions that increase the risk of stroke.

Atrial fibrillation (AF) is the most common heart rhythm disturbance, affecting approximately 1.6 meters people in the UK.

But after somebody has a stroke, it is often discovered.

The British Heart Foundation said that this study could pave the way for a better way to find people with AF and targeted treatments.

At the moment, electrocardiogram (ECG), which measures your electrical activity of your heart, is usually used to refer patients to atrial fibrillation.

Studies have found that three clinical risk factors and two biomarkers have a strong connection with AF, by researchers from Birmingham University.

Most people in the risk of condition were elderly, male and had a high BMI.

Researchers looked at 638 hospital patients recruited between 2014 and 2016 for acute ailments.

They took samples of blood and found 40 cardiovascular biomarkers and thought of seven clinical risk factors – age, race, hypertension, heart failure, stroke history or transient ischemic attack, kidney function and body mass index (BMI).

All of them were also given an echocardiogram.

Researchers discovered that two biomarkers came out as a link to atrial fibrillation.

One is a secret hormone by heart called brain naturally peptide (BNP) and the second is responsible for protein phosphate regulation, which is called fibroblastic growth factor -23 (FGF-23).

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Researchers say that whether these people have a high level of biomarkers to see if they can be tested for their blood tests.

Leading author Yuni Puri said: "The biomarkers we have identified have the ability to use blood tests in community settings such as to simplify patient selection for ECG screening in GP practice."

The joint first author, Dr. Winnie Chua, said: "People with Atrial Fibrillation are more likely to develop blood clots and suffer from stroke. It is important to take Anticocuentant medicines to stop blood clots for them to avoid stroke." Gtc: prefix = "" gtc: mediawiki-xid = The patient is diagnosed after facing a stroke.

"It is therefore important that patients with risks be tested so that they can start taking anticoagulants to prevent possible life-threatening complications."


Features of Atrial Fibrillation

  • Notably heartbeat, when heart looks like it is sharp, blurred or defeats
  • Your heart beat very quickly (often more than 100 beats per minute)
  • You can work your heart rate by checking your neck or wrist pulse.
  • Other symptoms may include tiredness and less ability to exercise, breathlessness, opacity or lightness and chest pain.
  • The way the heart pumps in the Atrial fibrillation reduces the functioning and functioning of the heart
  • This can lead to less blood pressure (hypotension) and heart failure
  • If you see a sudden change in your heart and feel chest pain, then you should immediately get your GP. Should look
  • Sometimes atrial fibrillation does not produce any symptoms and the person who has it is completely unaware that its heart rate is irregular.

Source: NHS England


British Heart Foundation's Associate Medical Director Professor Matin Avakir welcomed this study.

"Atrial fibrillation increases the risk of stroke, which is a serious condition that causes 36,000 deaths every year in the UK, but is often delayed. In this research, modern statistical and machine learning methods are used to analyze and encourage patient data. Evidence suggests that the combination of easy-to-measure indices is used to predict an atrial fibrillation.

"This study can help people with AF to prevent stroke and its catastrophic results and pave the way for their targeted treatment with blood-related drugs."

This research was done by the Institute of Cancer and Genetic Sciences at the University of Burdhamskullar Science Institute and the University of Birmingham College of Medical and Dental Sciences and published in the European Heart Journal.


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