Thursday , July 29 2021

Studies of immune reactions in environmental exposure at the beginning of life



Washington DC, Nov 24: Environmental exhibitions – such as objective factors, farm dust and air pollution – can trigger immune response in adolescents in early life.

Eastern Finland Research University has published the journal Pediatric Allergy and Immunology.

There is strong evidence that various early life shows may change the risk of allergic diseases. One of these is open farming. Disclosing the decrease in the risk of allergic diseases in childhood and exposing the farm environment in the environment.

On the other hand, known as the risk factor born by the cesarean section. The role of other maternal factors is studied less. Other harmful contact is air pollution, and especially in terms of particle contact, which is shown to increase asthma in children and increase intensity. However, mechanisms underlying are unclear, which delay the development of asthma-preventative strategies.

Earlier studies have shown that immunological development and maturity already started in pregnancy and early childhood. Therefore, reactions to this critical issue of immune development can improve immune response and cells, and thus affect the risk of allergy and other immune diseases.

Studies have shown that asthma-related immune responses change in different different children during pregnancy, birth, or childhood. The study focused on three different exhibits: an asthma-protective (farming) and two that lead to asthma (Caesarian department and air pollution).

"We have studied whether dendritic cells are associated with farming, asthma or atopoeo, residual factors affect immune response in adolescence in children born by the cesarean section, and whether there is immune effects on immune cells in the circulation of children in relation to farm dust and urban air particles. Is there. " Maria Viola Martínez

Study Environmental Contact was associated with asthma related immune reactions. A link between farm exposure and subsets of study, and the association between this subset and asthma in farmers' children suggests that these subset farm plays a role in related immunoglougration.

On the other hand, lack of natural birth processes during delivery and newborn intensive care treatment leads to long-lasting changes in immune responses. The effect of the preventive effects of particles on the apparently exciting effects of disease deterioration and immune responses suggest that these exhibits can modify respiratory disease and allergens response, and partly to explain the differences in the spread of asthma in the study environment.

This study demonstrated ex-organizations, former vivos and in vitro among various early life exhibitions and immune reactions. Some changes in immune response seemed observable until adolescence. This study has published some potential immunological mechanisms behind the various knowledge of advanced exhibitions and immunological mechanisms that either preserve or predict asthma.


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